Conape® is a brand name of the generic drug Perindopril. It is a
prescription only ACE inhibitor. This drug is commonly prescribed in
hypertension, heart failure and heart attacks. Conape dilates arteries and
reduces blood pressure by a complex mechanism. It also reduces the
workload of the heart. Reduced workload of the heart prevents future heart
attacks.
What are the common side effects?
Dry cough is the
most troublesome side effect. Changing to a drug like Lorsatan (Corsaar®)
(Angiotensine receptor blocker) can alleviate this side effect. Serum potassium
levels can go up with this medication. So the doctor may check patient’s
electrolyte levels in the blood before starting Conape.
Certain patients
can get dizziness and low blood pressure. Gastro intestinal disturbances like
nausea and vomiting are also common side effects. This drug is a potent
antihypertensive, so patient can get faintishness especially in the first few
days of the treatment. Muscle cramps are common with this drug. It is usually caused
by electrolyte imbalance.
What are the
serious side effects?
Very few
patients can get an allergic reaction to this medication. Sometimes it can lead
to an anaphylactic shock. This is characterized by wide spread hives, chest
tightness, low blood pressure, shortness of breath and pallor. Patient should
stop the medication and seek immediate medical help.
What are the
uncommon side effects?
Chest pain, edema,
flatulence, nervousness, depression, sleep problems, blurred vision, impotence
and back pain are relatively uncommon side effects. Other less common side
effects include reduced white cell counts, pancreatitis, cardiac rhythm
abnormalities, headache and dizziness.
Few patients may
get shortness of breath and muscle/joint pains with this medication. This
medication is also known to cause upper respiratory tract infections in certain
patients.
What the doctor
should know before prescribing Conape?
Before starting
this medication doctor should know patient’s complete medical history,
including over the counter medication he/she is on. If the patient has
following conditions then he/she must discuss with the doctor before taking Conape.
1. Bilateral renal artery stenosis
2. Heart disease called Aortic or Mitral
valve stenosis
3. Hypertrophic cardiomyopathy
4. Liver diseases
What about pregnancy and breast feeding?
If the
patient is pregnant or nursing, doctor will not prescribe Conape. Taking Conape
in a pregnancy can harm the unborn baby.
What are the
things patient should know before taking Conape?
Do not take over the
counter NSAID pain killers such as Diclofenac sodium, Brufen without consulting
your doctor. This medication should be taken as a whole with full glass of
water and it should not be crushed to minimize side effects. Conape can be
taken with or without meals. This medication should also be taken strictly as
instructed. Do not share this medication with anyone. Keep this medication out
of reach of children.
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